For Horse Owners
Vet administered, equicenta® CTM is derived from equine umbilical cord tissue and engineered to support joints, tendons, and ligaments with nature’s own design — from horses for horses.
Our peer-reviewed trial in Frontiers in Veterinary Science is live, the largest controlled trial of its kind in equine regenerative medicine.
For Which Horses
equicenta® CTM is designed to support equine joints, tendons, and ligaments — the tissues that take the heaviest load in any career, from foal to senior, sport horse to companion. Whether it’s appropriate for your horse depends on the diagnosis, the lesion, and the plan your veterinarian builds with you.
It is intended as part of a broader, structured plan — not a stand-alone fix.
See the Clinical Detail
What’s Inside
equicenta® CTM is built from naturally-occurring proteins found in equine umbilical cord tissue. Each one plays a specific role — and each one has a story. Tap any name below for the plain-language version.
View All TwelveYour horse’s built-in structural support beams. Collagens form the backbone of bone, tendon, ligament, and cartilage — they’re what holds everything in working order under load.
Read the full story →The cushion layer that organizes the matrix and holds water. They’re what gives joints and tendons their bounce, stride after stride.
Read the full story →Why a healthy joint feels springy, not stiff. GAGs keep the joint hydrated and lubricated — the perfect saddle pad that never packs down.
Read the full story →The protein that tells the demolition crew to put down the sledgehammers. A2M binds enzymes that break down cartilage and tendon, and reins in chronic damage.
Read the full story →Inflammation that doesn’t resolve is what turns a one-time injury into a chronic problem. Annexin is part of how the body shuts inflammation off on time.
Read the full story →Tangled collagen fibers heal as scar. Aligned collagen fibers heal as functional tissue. Decorin is what does the lining-up — a small protein with an outsized job.
Read the full story →Repair cells with no direction re-injure. Transgelin signals to fibroblasts and stem cells, helping them rebuild smarter, not just harder.
Read the full story →Stalls don’t fail because the wood breaks — they fail because the hinges pull out. Vinculin is the heavy-duty hardware holding cells to the matrix around them.
Read the full story →The proteins that show up after the storm and rebuild it right — straight fences, level footing, gates back where they belong. Organized rebuild, not scar.
Read the full story →An active injury site is a hostile place for cells. Clusterin shields them so they can keep doing repair work through the worst of it.
Read the full story →Most chronic joint problems aren’t a healing problem — they’re a stopping problem. IL-1ra and IL-10 are the body’s most important brakes on inflammation.
Read the full story →Tissue can’t heal without supply. VEGF is the signal that tells the body to build the roads — new blood vessels — to deliver everything healing tissue needs.
Read the full story →Connect us with your veterinarian so we can discuss case study opportunities.
Connect Us With Your Vet
Now Published
In a published, open-label controlled trial (Bertone et al., 2026), a single injection of equicenta® CTM was associated with 2.72:1 odds of returning to prior performance. Injection reactions were reported after 3.4% of equicenta® CTM injections and 10.5% of standard-of-care injections.
Study limitations: open-label design; heterogeneous, clinician-selected comparator; funded by Equine Performance Labs.
For use by or on the order of a licensed veterinarian. Not for use in humans.
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