equicenta® CTM — Equine Performance Labs
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equicenta® CTM

Developing the New Standard in Equine Musculoskeletal Tissue Support

equicenta® CTM is part of a broader commitment to raise the bar for equine biologics.

Now
Published

Our peer-reviewed trial in Frontiers in Veterinary Science is live, the largest controlled trial of its kind in equine regenerative medicine.

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equicenta® CTM

What is equicenta® CTM?

equicenta® CTM is a cryopreserved equine umbilical-cord-tissue allograft. Supplied as a single, ready-to-use dose, it eliminates the need for an autologous blood draw, chairside processing, or corticosteroid administration.

Unlike an acellular fluid, such as plasma, that disperses following injection, equicenta® CTM retains a native fetal extracellular-matrix scaffold at the treatment site. This scaffold contains a characterized multimodal structural proteins, growth factors, cytokines, and extracellular vesicles. The retained matrix is designed to provide structural support and progressively release its biological components over time, supporting a local environment associated with the body’s natural tissue-repair processes.

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Cryopreserved equicenta CTM tissue matrix
Joint synovium and tissue matrix illustration

BMC Medicine, 2025

Safety Study

In published characterization (Bertone et al., BMC Medicine, 2025), equicenta® CTM was found to contain:

  • Structural ECM components (collagens, proteoglycans, GAGs)
  • Anti-inflammatory mediators (IL-1ra, IL-10)
  • Growth factors (VEGF)
  • Protease inhibitors (A2M)

The paper also reports a controlled biocompatibility study in 8 clinically normal horses over 42 days. This controlled biocompatibility study does not establish efficacy. equicenta® CTM is investigational; absolute safety has not been established.

Frontiers in Veterinary Science, 2026

Clinical Study

In a published, open-label controlled trial (Bertone et al., 2026), equicenta® CTM was compared with clinician-selected, non-steroidal standard-of-care biologics in 138 horses with 195 conditions at 8 U.S. specialty equine practices, with a 26-week performance endpoint. Injection reactions were reported after 3.4% of equicenta® CTM injections and 10.5% of standard-of-care injections.

Frontiers in Veterinary Science · 2026

138horses
195conditions
26weeks

Source: Bertone AL, et al. Front. Vet. Sci. 2026.

Exclusive Sourcing

Partner: Coteau Grove Farms

We partner directly with our source — a premier Louisiana breeder of registered racehorses. Our teams work closely to ensure our product is derived from full-term, natural deliveries within a single-source herd, maintaining the highest standards for mare and foal welfare.

Coteau Grove Farms: Founded in 2008 by Keith and Ginger Myers, Coteau Grove Farms delivers exceptional, personalized care while breeding top-tier Louisiana-bred racehorses that compete—and win—nationwide. With champions like No Parole and Touchupsmaster, and a steady infusion of elite bloodlines, the farm continues to produce winners year after year.

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Coteau Grove Farms mare and foal
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