equicenta® CTM
equicenta® CTM is part of a broader commitment to raise the bar for equine biologics.
equicenta® CTM
equicenta® CTM is a microparticulate connective tissue matrix derived from equine umbilical cord (Wharton’s jelly), processed under ISO-aligned quality standards.
Designed for use by veterinarians in:
equicenta® CTM
equicenta® CTM is a dual-phase mechanism:
Phase 1: Immediate release of bioactive proteins
Phase 2: Gradual matrix remodeling as the scaffold integrates
It delivers:
This creates a non pro-inflammatory, scaffold-based environment that supports tissue homeostasis.
Get More InformationA side-by-side comparison of equicenta® CTM against the major categories of equine joint, tendon, and ligament therapies.
| Feature / Benefit | equicenta® CTM (Umbilical Tissue Allograft) Flagship |
Blood/Marrow Derived Plasma/Platelet Products |
Polysulfated Glycosaminoglycans (PSGAGs) | Polyacrylamides |
|---|---|---|---|---|
| Anti-inflammatory cytokines | IL-1ra, IL-10, A2M | IL-1ra, A2M | ||
| Regenerative growth factors | TGF-β, VEGF, IGF, FGF; includes Fetal Tissue Growth Factors | Variable; patient-limited; limited to soluble blood proteins | ||
| Structural ECM proteins | Collagens, decorin, biglycan, versican | |||
| Glycoproteins & proteoglycans | Integrins, annexins, PSGAGs, many proteoglycans | PSGAGs | ||
| Antioxidants & protective proteins | Superoxide dismutase, clusterin, heat shock proteins | |||
| Chondroprotective agents | TIMP-1, TIMP-2 (Tissue Inhibitor of Metalloproteinases), A2M | A2M | ||
| Batch consistency | <5% (low) variation across donors | Variable; patient-limited | ||
| Source | Allogeneic umbilical tissue; closed herd; healthy fetal origin | Autologous; typically abnormal adult | Semi-synthetic | Synthetic polymers |
| How it works | Dual-phase anabolic and anti-catabolic: immediate soluble + sustained matrix release. Super-majority of product is pro-regenerative. | Immediate soluble only; small fraction of product is pro-regenerative | Anti-metalloproteinase | Cushion: thickens synovium |
| Scaffold function | Natural ECM scaffold for tissue repair | No scaffold | No scaffold | |
| Method of degradation | Natural local biodegradation | Protein clearance | Non-degradable |
equicenta® CTM vs. Blood/Marrow Products
| equicenta® CTM Flagship |
Blood/Marrow Derived Plasma/Platelet Products |
|---|
A breakdown of the safety profile, peer-reviewed evidence, and ongoing clinical work that supports equicenta® CTM in practice.
Published in BMC Medicine. Backed by peer-reviewed safety data with a strong track record in clinical use.
View ArticleValidated across 140+ clinical cases with no significant adverse reactions reported.
View Clinical CasesSupported by veterinary research with published insights into how it works.
View MoreOngoing studies and expanded clinical data continue to reinforce its performance.
View ArticleExclusive Sourcing
We partner directly with our source — a premier Louisiana breeder of registered racehorses. Our teams work closely to ensure our product is derived from full-term, natural deliveries within a single-source herd, maintaining the highest standards for mare and foal welfare.
Coteau Grove Farms: Founded in 2008 by Keith and Ginger Myers, Coteau Grove Farms delivers exceptional, personalized care while breeding top-tier Louisiana-bred racehorses that compete—and win—nationwide. With champions like No Parole and Touchupsmaster, and a steady infusion of elite bloodlines, the farm continues to produce winners year after year.
Learn More

Day 0 Grade 3 RF lameness, blocked to foot — tracking response over time.
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Severe LF lameness with prior ligament intervention — complex case, structured response.
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Before the ribbons, before the results — one rider’s journey back.
Read More
The structural protein behind every tendon, ligament, and joint — explained simply.
Read More“In cases like severe synovitis and collateral ligament injury, equicenta® CTM produced faster, more complete responses than I typically see with other treatments.Dr. Lacher Read More
“Before the ribbons, before the results — Vivi’s journey through injury, recovery, and return to work.Vivi’s Story Read More
“After tearing the tendon in his front leg, we weren’t sure who Moo would be on the other side—but with equicenta® CTM, we got him back.Teri T. Read More
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