equicenta® CTM — Equine Performance Labs

equicenta® CTM

The New Standard in Equine Musculoskeletal Tissue Support

equicenta® CTM is part of a broader commitment to raise the bar for equine biologics.

equicenta® CTM

What is it?

equicenta® CTM is a microparticulate connective tissue matrix derived from equine umbilical cord (Wharton’s jelly), processed under ISO-aligned quality standards.

  • No cultured cells
  • Ready-to-inject suspension
  • Delivered in 1.5 mL dose

Designed for use by veterinarians in:

  • Joints
  • Tendons
  • Ligaments
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Cryopreserved equicenta CTM tissue matrix
Joint synovium and tissue matrix illustration

equicenta® CTM

How does it work?

equicenta® CTM is a dual-phase mechanism:

Phase 1: Immediate release of bioactive proteins

Phase 2: Gradual matrix remodeling as the scaffold integrates

It delivers:

  • Structural ECM components (collagens, proteoglycans, GAGs)
  • Anti-inflammatory mediators (IL-1ra, IL-10)
  • Growth factors (VEGF)
  • Protease inhibitors (A2M)

This creates a non pro-inflammatory, scaffold-based environment that supports tissue homeostasis.

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Why equicenta® CTM vs. common alternatives

A side-by-side comparison of equicenta® CTM against the major categories of equine joint, tendon, and ligament therapies.

Feature / Benefit equicenta® CTM
(Umbilical Tissue Allograft)
Flagship
Blood/Marrow Derived
Plasma/Platelet Products
Polysulfated Glycosaminoglycans (PSGAGs) Polyacrylamides
Anti-inflammatory cytokinesIL-1ra, IL-10, A2MIL-1ra, A2M
Regenerative growth factorsTGF-β, VEGF, IGF, FGF; includes Fetal Tissue Growth FactorsVariable; patient-limited; limited to soluble blood proteins
Structural ECM proteinsCollagens, decorin, biglycan, versican
Glycoproteins & proteoglycansIntegrins, annexins, PSGAGs, many proteoglycansPSGAGs
Antioxidants & protective proteinsSuperoxide dismutase, clusterin, heat shock proteins
Chondroprotective agentsTIMP-1, TIMP-2 (Tissue Inhibitor of Metalloproteinases), A2MA2M
Batch consistency<5% (low) variation across donorsVariable; patient-limited
SourceAllogeneic umbilical tissue; closed herd; healthy fetal originAutologous; typically abnormal adultSemi-syntheticSynthetic polymers
How it worksDual-phase anabolic and anti-catabolic: immediate soluble + sustained matrix release. Super-majority of product is pro-regenerative.Immediate soluble only; small fraction of product is pro-regenerativeAnti-metalloproteinaseCushion: thickens synovium
Scaffold functionNatural ECM scaffold for tissue repairNo scaffoldNo scaffold
Method of degradationNatural local biodegradationProtein clearanceNon-degradable

equicenta® CTM vs. Blood/Marrow Products

equicenta® CTM
Flagship
Blood/Marrow Derived
Plasma/Platelet Products

Safety & Contraindications

A breakdown of the safety profile, peer-reviewed evidence, and ongoing clinical work that supports equicenta® CTM in practice.

Proven Safe

Published in BMC Medicine. Backed by peer-reviewed safety data with a strong track record in clinical use.

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Real-World Results

Validated across 140+ clinical cases with no significant adverse reactions reported.

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Science-Driven

Supported by veterinary research with published insights into how it works.

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Built on Evidence

Ongoing studies and expanded clinical data continue to reinforce its performance.

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Exclusive Sourcing

Partner: Coteau Grove Farms

We partner directly with our source — a premier Louisiana breeder of registered racehorses. Our teams work closely to ensure our product is derived from full-term, natural deliveries within a single-source herd, maintaining the highest standards for mare and foal welfare.

Coteau Grove Farms: Founded in 2008 by Keith and Ginger Myers, Coteau Grove Farms delivers exceptional, personalized care while breeding top-tier Louisiana-bred racehorses that compete—and win—nationwide. With champions like No Parole and Touchupsmaster, and a steady infusion of elite bloodlines, the farm continues to produce winners year after year.

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Coteau Grove Farms mare and foal

For Vets

Explore clinical data, protocols, and product details.

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For Owners

Learn if this may be right for your horse.

Explore for Owners

Real horses. Real decisions.

In cases like severe synovitis and collateral ligament injury, equicenta® CTM produced faster, more complete responses than I typically see with other treatments.
Dr. Lacher Read More
Before the ribbons, before the results — Vivi’s journey through injury, recovery, and return to work.
Vivi’s Story Read More
After tearing the tendon in his front leg, we weren’t sure who Moo would be on the other side—but with equicenta® CTM, we got him back.
Teri T. Read More

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